Spectrophotometric Determination of Binding Constants of Ru(III) Salicylideneimine Complexes with CT DNA

Abstract

The interactions of Ru(III)  complexes with Schiff bases derived from salicylaldehyde and aminophenol, butylamine and naphthylamine with general formula Na[Ru(N-R-5-X-salim)₂] (R = C₆H₄O, X = H, Cl, Br, NO₂), Na[RuCl₂(N-R-5-X-salim)₂] (R = C₄H₉, X = H, Cl, Br, NO₂) and [Ru(N-R-5-X-salim)₃] (R = C₁₀H₇, X = H, Cl, Br) with CT DNA, were investigated by spectroscopic titration. Experimental data show that Ru(III) complexes with salicylideneimine bind CT DNA with constants of 10⁴ M^-1. The results indicate the influence of 5-X-substituents on K_b values.