Determination of Clindamycin Hydrochloride Content in 1% Clindamycin Lotion

Abstract

UV-Vis spectrophotometric analysis was performed on extemporaneous 1% clindamycin lotion preparations from pharmacy samples. The content of clindamycin hydrochloride varied significantly from 21% to 142%, indicating considerable quality control inconsistencies in the preparation of these pharmaceutical products.