Synthesis, characterization and in vitro antimicrobial activity of the Cu(II) and Fe(III) complexes with 1-cyclopropyl-6-fluoro-4-oxo-7-(piperazin-1-yl)-1,4-dihydroquinoline-3-carboxylic acid

Abstract

The interactions of ciprofloxacin with Cu(II) and Fe(III) ions were examined under physiological conditions. The synthesized complexes underwent IR spectroscopy and stereo-microscopy analysis. Testing on bacterial strains (Escherichia coli, Enterococcus faecalis, Staphylococcus aureus, and Salmonella Enteritidis) revealed that Cu(CFL)2 complex showed better antimicrobial activity compared to the Fe(CFL)2(H2O)2 complex.