Synthesis and biological evaluation of xanthen-1,8-dione derivatives

Abstract

Fourteen xanthen-1,8-dione derivatives underwent screening for antimicrobial, antiproliferative, and antioxidant properties against various bacterial strains and fungal species. Testing evaluated compound effects on multiple cell lines. The investigation found that brominated compounds demonstrated potent antimicrobial activity, while a methoxy-hydroxy-nitrophenyl derivative exhibited superior antioxidant capacity.