Qualitative and quantitative determination of ligustilide as bioactive marker in apiaceous botanicals

Abstract

Ligustilide content was analyzed in four plant species using nuclear magnetic resonance spectroscopy following supercritical CO2 extraction. Results showed varying ligustilide percentages: L. porteri (3.74%), L. sinense (1.16%), L. striatum (6.61%), and A. sinensis (14.56%). Despite L. porteri yielding the greatest essential oil volume, A. sinensis contained the highest ligustilide concentration. The compound exhibits diverse pharmacological properties including anti-inflammatory and neuroprotective effects.